Adenocarcinoma of rectum metastatic to eye: report of case

Abstract

A 64-year-old man with a history of low grade adenocarcinoma of rectum 2 years previously, presented with decrease of the visual field of the left eye. Examination revealed an intraocular tumor located at the posterior pole and total retinal detachment. The patient was submitted to an enucleation. In the macroscopy, to the serial sections was observed an exophytic tumor of light brown color of 2 × 1.4 × 7 cm, located in posterior chamber with hematic content. Histopathology showed infiltration by tubular moderately differentiated adenocarcinoma of intestinal type, which compromised the vitreous chamber, retina, choroid and partially infiltrated the sclera, exceeded the lamina cribrosa and invaded the optic nerve. The neoplastic cells were positive for CDX-2. The intraocular metastasis is preferably located in the choroid being more frequently adenocarcinomas from the lung and breast and being very rare metastatic adenocarcinomas from colon or rectum. A 64-year-old man with a history of low grade adenocarcinoma of rectum 2 years previously, presented with decrease of the visual field of the left eye. Examination revealed an intraocular tumor located at the posterior pole and total retinal detachment. The patient was submitted to an enucleation. In the macroscopy, to the serial sections was observed an exophytic tumor of light brown color of 2 × 1.4 × 7 cm, located in posterior chamber with hematic content. Histopathology showed infiltration by tubular moderately differentiated adenocarcinoma of intestinal type, which compromised the vitreous chamber, retina, choroid and partially infiltrated the sclera, exceeded the lamina cribrosa and invaded the optic nerve. The neoplastic cells were positive for CDX-2. The intraocular metastasis is preferably located in the choroid being more frequently adenocarcinomas from the lung and breast and being very rare metastatic adenocarcinomas from colon or rectum.