Abstract
BackgroundMetastasis to the urinary bladder from gastric cancer is rare. Metastasis to a diverticulum of the bladder from gastric cancer is extremely rare. We report a case of isolated bladder metastasis from gastric cancer and invasion localized to the muscularis propria of the primary site (stomach).Case presentationA 90-year-old female presented with nausea and vomiting that was diagnosed as gastric cancer, the patient also had intermittent hematuria. Pelvic computed tomography identified an abnormally thickened area in the bladder wall that was diagnosed as a diverticulum of the bladder. A biopsy of the bladder wall revealed well differentiated tubular adenocarcinoma metastatic from gastric carcinoma.ConclusionAlmost all cases of bladder metastasis from gastric cancer had peritoneal dissemination. This particular presentation of bladder metastasis from gastric cancer, to the best of our knowledge, has not been previously reported.
Highlights
Metastasis to the urinary bladder from gastric cancer is rare
The bladder may be involved in the late stages from metastasis and is usually associated with metastasis to other organs [3], but isolated bladder metastasis and invasion localized in the muscularis propria of the primary site is extremely rare
Cystoscopy was performed which showed a lesion in the bladder diverticulum, a biopsy of the bladder wall revealed well-differentiated tubular adenocarcinoma metastasis from gastric carcinoma
Summary
Metastasis to a diverticulum of the bladder from gastric cancer is extremely rare [1]. A-90-year-old female presented in November 2003 with a history of nausea, vomiting and dysphagia, with hematuria On admission her abdomen was slightly distended, tympanic, and slightly tender in the upper abdominal regions, with normal bowel sounds and no palpable mass. A biopsy of the stomach was taken which revealed well-differentiated tubular adenocarcinoma. Cystoscopy was performed which showed a lesion in the bladder diverticulum, a biopsy of the bladder wall revealed well-differentiated tubular adenocarcinoma metastasis from gastric carcinoma. Histology revealed well differentiated tubular adenocarcinoma invading to the muscularis propria (MP), 3type, Infiltrative growth pattern (inf) β, int, ly, v0 Patient later developed pyelonephritis, bilateral hydronephrosis, disseminated intravascular coagulation (DIC) and died three months after the surgery
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