Abstract
Recent observations and theories implicating long-wave ultraviolet radiation (320-400 nm) as the stimulus for various phenomena in human skin have prompted us to investigate the erythemogenic properties of middle (UV-B) and long (UV-A) wave ultraviolet light combinations. The backs of fair-skinned human volunteers were irradiated with varying doses of UV-A and UV-B to determine the minimal perceptible erythema (MPE) dose in each of these wavelength regions. The subjects then received overlapping suberythemal doses of UV-A and UV-B in each of several sites. When UV-A was held constant and UV-B was varied, the observed breakpoint dose (energy at which MPE was seen in doubly irradiated sites) quantitatively demonstrated an additive phenomenon. When combined energies approach threshold erythema values, the known erythemogenic properties of high-dose UV-A are additive to the subclinical or visible erythema induced by UV-B.
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