Abstract

Fungal fatty acids: The synthesis of fatty acids is an essential primary metabolic process for energy storage and cellular structural integrity. Fungal fatty acid synthases (FASs) are unusual among FASs and self-pantetheinylate to their active holo-form. Dissection of the FAS α-subunit involved in aflatoxin biosynthesis and in vitro assays with purified proteins revealed the activation partnerships in the aflatoxin biosynthetic pathway.

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