Abstract

Acute toxicity test involves estimation of LC50 or LD50 which is the concentration or dose which proved to be lethal causing death to 50% of the tested organisms. This article reviews the methods utilized for the determination of Probit and LC50 and also explain the use of Minitab 14 statistical package and Microsoft office excel 2007 for accurate, speedy and qualitative presentation of toxicity results. We also present a brief review on the relationship between uptake route of toxicants and their toxic effects.

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