Abstract
Ivermectin (22,23-dihydroavermectin B1a and B1b), as the commercial Premix for Pigs, was found to be acutely toxic to the marine sediment-dwelling polychaete Arenicola marina (10-day LC50 0.023 mg/kg dry weight of sediment, confidence limits 0.018 and 0.027 mg/kg). At all concentrations tested (i.e., 0.006 mg/kg dry weight and above), ivermectin reduced the rate of cast production. Prior exposure to 0.010 mg/kg or more reduced the rate at which A. marina was able to rebury in clean sediment. The results indicate that there is a clear case for targeted field studies at marine salmon farming sites where permission may be given to use ivermectin to control ectoparasitic sea lice infections.
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