Abstract
Acute hemolytic crisis in a patient with hemoglobin constant spring disease: a case report
Highlights
Acute hemolytic crisis is characterized by the sudden drop of hemoglobin level with signs of red blood cell (RBC) destruction such as an increased indirect bilirubinemia and signs of compensated RBC production such as an increased polychromasia
It can complicate any chronic hemolytic anemia Hb H disease if the patients expose to oxidation, for instance, the high fever from an infection [2]
The acute hemolytic crisis has been the very rare complication in Hb Constant Spring (CS) disease even in the areas of high prevalence of Hemoglobin Constant Spring (Hb CS) such as Thailand [5] or Malaysia [6], Hb can drop from 10.7 g% at the steady state to 5.0 g% during the crisis from viral infection [6]
Summary
Acute hemolytic crisis is characterized by the sudden drop of hemoglobin level with signs of red blood cell (RBC) destruction such as an increased indirect bilirubinemia and signs of compensated RBC production such as an increased polychromasia. The destruction is more rapid than the production [1] It can complicate any chronic hemolytic anemia Hb H disease if the patients expose to oxidation, for instance, the high fever from an infection [2]. The acute hemolytic crisis has been the very rare complication in Hb CS disease even in the areas of high prevalence of Hb CS such as Thailand [5] or Malaysia [6], Hb can drop from 10.7 g% at the steady state to 5.0 g% during the crisis from viral infection [6]. We report an additional case of acute severe hemolytic crisis in the patient who was later proved to harbor Hb CS disease
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
