Abstract

<p>The objective of the research was to evaluate the antibacterial activity of five terpenoid compounds: carvacrol, limonene, linalool, α-terpinene and thymol in Gram negative bacteria (<em>Escherichia coli, Salmonella </em>spp<em> </em>and<em> Pseudomona </em>spp) and Gram positive (<em>Staphylococcus aureus </em>and<em> Streptococcus </em>spp). The antibacterial activity was determined by the disk diffusion method on Mueller-Hinton agar; as controls were used alcohol 70% and two antibiotics (ceftibuten and cephalexin) were used for Gram negative and positive bacteria respectively. Were made five concentrations of 0.75, 0.45, 0.15, 0.075 and 0.05 mg mL<sup>-1</sup> for the terpenoids compounds and antibiotics. The largest inhibition zone were presented with carvacrol (5.5 mm), linalool (6 mm) and thymol (5.5 mm) in the bacteria <em>Salmonella </em>spp, <em>S. aureus</em> and <em>E. coli</em> respectively. The bacteria most sensitive to the terpenoids were <em>E. coli</em>, <em>Salmonella </em>spp and <em>S. aureus</em> while the most resistant bacteria were <em>Pseudomona </em>spp and <em>Streptococcus </em>spp<em>.</em> It is concluded that there is no difference in antibacterial activity among the five terpenoids compounds when exposed to Gram negative and positive bacteria, except when evaluated with <em>S. aureus</em> bacteria where carvacrol, limonene and linalool have an antibacterial effect similar to that of cephalexin antibiotic. </p>

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