Abstract
To establish the optimal dose and sampling times for the ACTH stimulation test in racing pigeons, plasma corticosterone concentrations were measured in experimental animals at 0, 30, 60, 90, 120 and 150 min after intramuscular administration of different doses of ACTH(1-24). Baseline corticosterone concentrations varied between less than 0.2 and 1.24 microg/dl. To evaluate adrenocortical function the clinician is advised to take a blood sample before and at 60 or 90 min after stimulation with 50 microg ACTH or at 30, 60, 90 or 120 min after stimulation with 125 mug ACTH. In healthy individuals a ten- to hundred-fold increase over baseline (t=0) corticosterone concentrations and absolute concentrations in the range of 2.2 to 15.0 microg/dl can be expected in the post stimulation sample.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
