Abstract
The analysis of the actin cytoskeleton reorganization of bone marrow multipotent mesenchymal stromal cells (MMSCs) of rat after hour adhesion to a monolayer of endothelial cells (ECs) line EA.hy 926 allowed us to identify three types of cells interacting with the ECs. Approximately half of MMSCs retained a rounded shape, most of them contained large round actin aggregates, had irregular borders and contacted with the surface of the ECs microvilli or protrusions similar to small lamellae. Almost all other cells were surrounded around of narrow lamellae. In addition, were seldom observed flattened elongated cells that contacting with ECs by means of focal contacts. Microenvironment factors, such as proinflammatory cytokine tumor necrosis factor α or plasma proteins affected the ratio different types of stromal cell types.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
