Abstract
Acral (limb) and renal anomalies occur together as a single developmental field defect or as components of several malformation syndromes. The embryogenesis of that defect was studied experimentally by Lash and the developmental relationship between kidneys and limbs has been reviewed by Buchta and Gilbert. The acral anomalies consist of split hand/ split foot, varying combination of oligodactyly, ectrodactyly, syndactyly, brachydactyly, polydactyly or fusion of carpal, tarsal, metatarsal bones of hands and feet. Urinary tract dysplasias are renal agenesis, duplication, ureteral hypoplasia, polycystic kidneys, hydronephrosis and bladder neck obstruction. The authors report three cases of acrorenal syndrome and discuss its clinical and laboratory findings.
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