Abstract
SINCE steroids have been reported to be involved in the metabolism of the mucopolysaccharides of the dermis1–3, it appeared interesting to investigate the effect of adrenalectomy on the amount of acid mucopolysaccharides and hexosamines in dermal connective tissue. The investigations were performed on young male rats of the CFE strain. Animals in the experimental group were adrenalectomized when 30 days old; they weighed 95–100 g at this time. Both adrenalectomized and control animals were purchased from Carworth Farms, Inc., New York City, Rockland County, New York. The animals were fed ad lib. ‘Wayne Lab Blox’ (mice and rats) diet. The adrenalectomized rats received 2 per cent sodium chloride in tap water, those of the control group were given tap water alone; both beverages were offered ad lib.
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