Abstracts From the College of American Pathologists 2025 Annual Meeting (CAP25)

This Special Section is a compilation of the lectures on gastrointestinal and pancreaticobiliary pathology presented at the 14th annual spring seminar of the Korean Pathologists Association of North America (KOPANA). This seminar was held in conjunction with the 104th annual meeting of the United States and Canadian Academy of Pathology (USCAP) from March 19–21, 2015, in Boston, Massachusetts. There are 6 articles presented in this Special Section. The first by Ahn and Park presents recent updates in gastric pathology, including a definition of gastric preneoplastic lesions, various morphologic types of gastric adenocarcinomas, and important histopathologic features of endoscopic submucosal dissection specimens. In the second, Bae and colleagues describe 2 different morphologic patterns of multistep carcinogenesis with implications for 3 different molecular pathways of carcinogenesis in colorectal cancers (CRCs). This article aims to provide a better understanding of the differences in CRCs affecting different colonic sites with regard to age of onset, sex, race, and geographic area, thus further elucidating the different clinicopathologic features of CRCs in association with the proposed molecular carcinogenesis pathways. Next, Lee and colleagues address various clinical and surgical aspects of idiopathic inflammatory bowel disease (IBD) that are pertinent to practicing pathologists. Also, topics such as IBD in patients with primary sclerosing cholangitis and the current status of IBD in Asia are briefly reviewed. The article by Jang and Ahn introduces the concept of tumoral and flat intraepithelial neoplasia to describe various premalignant lesions of the pancreatobiliary region. This dichotomous concept is proposed to further understand the biologic behavior of premalignant lesions of pancreatobiliary tract, ampulla of Vater, and gallbladder. The article outlines the histopathologic spectrum of changes encountered in tumoral and flat intraepithelial neoplasia, reflecting on the inherent differences in the genetic profiles of these groups of premalignant lesions. In the fifth article, Kim and Hong put forth recent updates on neuroendocrine tumors of gastrointestinal and pancreatobiliary tracts in concordance with the updates in this category of tumors proposed in the 2010 World Health Organization classification scheme. In this review, they address issues dealing with grading and prognostic markers of the neuroendocrine tumors. Finally, Wang and Park present a brief history of successes and failures of targeted therapeutic strategies for gastrointestinal malignancies. They also present information about the next generation of clinical oncology trial designs. The next 10 years of precision medicine oncology trials, which are guided by genomic testing of tumors, are certainly deemed to bear a significant impact on the practice of surgical pathology as it exists today. Pathologists have to equip themselves with the requisite skills to effectively deal with new emerging roles and responsibilities in this era of precision medicine. KOPANA was founded in 1992 and by 2001 had a membership of more than 200 Korean pathologists practicing in North America in a variety of venues such as universities, community hospitals, private laboratories, and research institutes. Currently, about 50 American pathologists of Korean heritage (Korean American pathologists) are KOPANA members and their number is growing. Now is an important transition time for KOPANA, as considerable numbers of our older members have retired or are approaching retirement. Fifteen years ago, KOPANA began convening its spring seminar in conjunction with the annual meeting of USCAP to provide opportunities for networking, education, and enjoyment for our members. Our spring seminar has always been an excellent educational event for both our members and pathologists from Korea. Each year our invited speakers include not only our Korean American members but also pathologists in Korea. This has been a perfect venue for professional networking between pathologists in 2 geographic areas. The Korean Society of Pathologists (KSP) was founded in 1946 and currently has about 1100 members. The KSP mission is to provide pathologists with high-quality continuing medical education (CME). This is accomplished by supporting a broad range of CME programs including spring and fall annual meetings, 16 subspecialty study groups, and 4 regional societies. The Journal of Pathology and Translational Medicine (http://www.jpatholtm.org) is KSP’s peer-reviewed, international scientific journal that is focused on introducing and evaluating new knowledge and methodologies. KSP also Accepted for publication October 14, 2015. From the Department of Pathology & Laboratory Medicine, University of Kentucky, Lexington (Dr Lee); the Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea (Dr Yu); and the Department of Pathology and Genomic Medicine, Houston Methodist Hospital and Weill Medical College of Cornell University, Houston, Texas (Dr Ro). The authors have no relevant financial interest in the products or companies described in this article. doi: 10.5858/arpa.2015-0381-ED Reprints: Jae Y. Ro, MD, PhD, Department of Pathology and Genomic Medicine, Houston Methodist Hospital, 6565 Fannin St, M227, Houston, TX 77030 (email: jaero@houstonmethodist.org).

Abstract and case study poster sessions will be conducted during the College of American Pathologists' Annual Meeting (CAP '07), which is scheduled for September 30 to October 3, 2007. The meeting will occur at the Sheraton Chicago Hotel & Towers, Chicago, Ill. The poster sessions will occur in the Connection Café and Exhibit Hall. Specific dates and times for each poster session are listed below. Also shown below each poster session listing are the subject areas that will be presented during each session.

The evolution of high complexity companion testing for targeted and immuno-oncology.

The Fifth Annual Meeting of the Japan Endocrine Pathology Society was held in September 2001. A highlight of the meeting was the participation of Japanese and American endocrine pathologists in a conference to consider the topic "The Determination of Clinical Outcomes for Parathyroid Carcinomas by Histological Evaluation of Invasive Growth." The discussion was centered around three cases of parathyroid carcinomas selected by the coordinator, Dr. Kameyama, and discussed by Drs. Ronald DeLellis, Ricardo Lloyd, and Kennichi Kakudo. In this article, we summarize their diagnoses and comments.

The College of American Pathologists (CAP) is dedicated to pathology and laboratory medicine quality. The CAP's Laboratory Accreditation Program, Proficiency Testing Program, Q-Probes and Q-Tracks, site-specific cancer checklists, webinars, annual meetings, and Advanced Practical Pathology series are all focused on providing superior patent quality. The CAP is synonymous with quality in pathology and laboratory medicine. As pathology practice becomes more sophisticated, the CAP's many programs will increasingly help pathologists provide appropriate, personalized patient care.

This special section represents the compiled lectures on gastrointestinal, liver, and pancreatic tumors presented at the 9th Spring Seminar of the Korean Pathologists Association of North America (KOPANA) held on March 18 to 20, 2010, in Washington, District of Columbia, in conjunction with the 99th Annual Meeting of the United States and Canadian Academy of Pathology (USCAP). Topics covered include a review of the molecular aspects of colorectal and pancreatic cancers, as well as an update on precursor and early lesions of hepatocellular carcinoma.In his article, Gyeong Hoon Kang, MD, addresses the following topics: (1) 4 molecular subtypes of colorectal cancer exist, which can be defined by the combination of CpG island methylator phenotype and microsatellite instability (MSI) status, with their own clinicopathologic features and precursor lesions; and (2) a geographic difference exists in MSI rate and BRAF mutation rate of colorectal cancers. In her article, Young Nyun Park, MD, PhD, addresses the morphologically recognizable lesions during hepatocarcinogenesis, which include dysplastic lesions (dysplastic foci and dysplastic nodule) and small cancerous lesions (≤2 cm in diameter) (early hepatocellular carcinoma [HCC] and small progressed HCC). Their pathologic features are discussed with emerging biomarkers.In the article by Seung-Mo Hong, MD, PhD, Jason Y. Park, MD, PhD, Ralph H. Hruban, MD, and Michael Goggins, MD, the authors review the genetic and epigenetic mechanisms of pancreatic cancer in the context of histologic features.KOPANA was founded in 1992 and has a membership of more than 200 Korean pathologists in North America who are practicing in a variety of venues such as universities, community hospitals, private laboratories, or research institutes. Currently, about 50 American pathologists of Korean heritage (Korean-American pathologists) regularly attend annual USCAP meetings and have KOPANA membership. This number is growing every year.Ten years ago KOPANA started the Spring Seminar in conjunction with the Annual Meeting of USCAP to provide networking, educational, and recreational opportunities for our members. Our Spring Seminar has been an excellent educational event with speakers selected from among Korean-American pathologists and pathologists practicing in Korea. This has become an ideal venue for professional networking between Korean-American pathologists and pathologists in Korea, particularly for pathologists-in-training (members of the Korean Society of Pathologists). Indeed, participation by young Korean pathologists continues to grow, both in our educational program and at the USCAP meeting.On behalf of KOPANA, we would like to express our appreciation to the editorial board of Archives of Pathology & Laboratory Medicine for the invitation to publish our meeting's lectures in this forum. We hope this special section will be of great benefit to both pathologists in Korea and readers of the Archives.

The Abstracts and Case Study Program is a competitive program sponsored by the Education Division of the College of American Pathologists (CAP). The program is designed to promote a broad range of research in pathology. It offers CAP junior members the opportunity to submit original research or unique case studies to their peers in a poster presentation format. Submissions to this program are evaluated by a juried panel. CAP junior members are eligible for cash awards for their presentations. The Abstracts and Case Study Program also provides a unique opportunity for residents to enhance research skills, develop writing proficiency, gain practical experience at presenting their findings, and contribute to the literature and advancement of pathology. Abstract and case study poster sessions were conducted at the CAP's Annual Meeting on September 11–13, 2005, in Chicago, Ill.

Abstract and case study poster sessions will be conducted during the College of American Pathologists Annual Meeting (CAP '09), which is scheduled for October 11 to October 14, 2009. The meeting will take place at the Gaylord National Resort, National Harbor, Maryland. The poster sessions will occur in the Connection Café and Exhibits Hall. Specific dates and times for each poster session are listed below. Also shown below each poster session listing are the subject areas that will be presented during that session.

and case study poster sessions will be conducted during the 2019 College of American Pathologists Annual Meeting (CAP19), which is scheduled for September 21 to 25, 2019. The meeting will take place at the Gaylord Palms Resort & Convention Center, Kissimmee, Florida. The poster sessions will occur in the CAP19 Exhibit Hall. Specific dates and times for each poster session are listed below; "poster focus" times are dedicated poster-viewing periods. Also shown before each poster session are the subject areas that will be presented.

and case study poster sessions will be conducted during the 2018 College of American Pathologists Annual Meeting (CAP18), which is scheduled for October 20 to 24, 2018. The meeting will take place at the Hyatt Regency, Chicago, Illinois. The poster sessions will occur in the CAP18 Exhibit Hall. Specific dates and times for each poster session are listed below; "poster focus" times are dedicated poster viewing periods. Also shown before each poster session are the subject areas that will be presented.

The College of American Pathologists (CAP) is dedicated to pathology and laboratory medicine quality. The CAP's Laboratory Accreditation Program, Proficiency Testing Program, Q-Probes and Q-Tracks, site-specific cancer checklists, webinars, annual meetings, and Advanced Practical Pathology series are all focused on providing superior patient quality. The CAP is synonymous with quality in pathology and laboratory medicine. As pathology practice becomes more sophisticated, the CAP's many programs will increasingly help pathologists provide appropriate, personalized care.

Progress in implementing HER2 testing guidelines.

Change in Pathology Medical Education: The Time Is Now.

Abstracts and Case Studies From the College of American Pathologists 2012 Annual Meeting (CAP '12)

Abstracts and Case Studies From the College of American Pathologists 2014 Annual Meeting (CAP '14)