Abstract P-019: COMPARISON BETWEEN SYNCHRONIZED AND NON-SYNCHRONIZED VENTILATION AND BETWEEN GUIDED AND NON-GUIDED CHEST COMPRESSIONS DURING RESUSCITATION IN A PEDIATRIC ANIMAL MODEL AFTER ASPHYXIAL CARDIAC ARREST

Abstract

Aims & Objectives: To compare between synchronized and non-synchronized bag-valve-mask ventilation (BVMV) with chest compression and between guided and non-guided chest compression (CC) with a real-time feedback-device in a pediatric animal model of asphyxial cardiac arrest (CA). Methods Experimental model of asphyxial CA in piglets. Piglets were randomized for cardiopulmonary resuscitation (CPR) into four groups according to BVMV (synchronized and non-synchronized with CC) and to CC feedback (with and without CC feedback accelerometer, ZOLL®): Group A, guided-CC and synchronized ventilation; B, guided-CC and non-synchronized ventilation; C, non-guided CC and synchronized ventilation; D, non-guided CC and non-synchronized ventilation. Systolic, diastolic and mean blood pressure (SBP, DBP and MBP), and return of spontaneous circulation (ROSC) were compared between all groups. Results 43 piglets (median weight 11.8 kg) were studied. Twenty (46.5%) achieved ROSC: group A 36.4%, group B 75%, group C 30% and group D 46.5% (p=0.13). Survival rates was higher in group B than in A+C+D (75% vs 35.5%, p=0.02). ROSC was higher with non-synchronized ventilation (B+D 59.1% vs A+C 33.3%, p=0.091) and with guided-CC (A+B 56.5% vs C+D 35%, p=0.16). BP after 3 minutes of resuscitation are shown in Table 1. Non-synchronized ventilation was associated with higher SBP and MBP. No significant differences were found regarding blood pressures between group B and the rest of groups.Conclusions In a pediatric animal model of CA, non-synchronized ventilation and guided CPR obtained significantly higher survival rates. Better SBP and MBP after 3 minutes of resuscitation were achieved with non-synchronized ventilation.