Abstract
Abstract In my presentation, I will describe an experimental strategy to reveal actionable protein domains that sustain the growth of cancer cells, which relies on CRISPR-Cas9-based indel mutagenesis of exons encoding protein domains. Citation Format: Christopher Vakoc. Cancer drug target identification using domain-focused CRISPR screening [abstract]. In: Proceedings of the AACR Conference on Advances in Sarcomas: From Basic Science to Clinical Translation; May 16-19, 2017; Philadelphia, PA. Philadelphia (PA): AACR; Clin Cancer Res 2018;24(2_Suppl):Abstract nr IA07.
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