Abstract
Absence of the cavum septum pellucidum is an unusual abnormality found in newborns that is associated with malformations of the brain. It is estimated that 2 to 3 individuals per 100,000 people in the general population have an absence of the cavum septum pellucidum. This anomaly can be associated with neurological anomalies such as optic nerve hypoplasia, holoprosencephaly, septo-optic dysplasia, abnormalities of the corpus callosum, and Chiari II malformation. It is rare to have an absent cavum septum pellucidum without any other brain anomalies.
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