Abstract
Root canals of dog and monkey teeth were filled with Sealapex, calcium hydroxide, or kerr Root Canal Sealer. As a control, some root canals were left empty. The animals were killed 6 months later and the specimens removed and prepared for histological analysis. There was no significant difference between reactions observed in the teeth of dogs as compared with those in monkeys. The results showed that Sealapex and calcium hydroxide encourage apical closure by cementum deposition. Closure was more frequently observed in cases with partial pulpectomy than in cases with total pulpectomy.
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