Abstract

Cultures of peripheral blood leukocytes were examined from ten persons occupationally exposed to γ-rays (total dose 7.7-36 rem over 7-15 years), ten persons occupationally exposed to fast neutrons and γ-rays (total dose 4.3-15.9 rem over 4-12 years) and ten normal subjects. No evidence of increased aneuploidy was noted for the exposed groups. In the gamma group dicentrics were observed in five of six persons, each with an accumulated dose in the range 12.8-36 rem. The incidence of chromosome aberrations was about 1% for all groups, and precluded an evaluation of a possible relationship between aberration yield and dose kinetics.

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