Abstract

Background: Cholangiocarcinomas are highly lethal and rare cancers that account for approximately 3% of all gastrointestinal cancers in the United States. The incidence in the United States is 8 per 100,000. Data from the SEER program suggest 15% of all liver diagnosed cancers are intrahepatic cholangiocarcinoma. Approximately 1/3 of patients are under age 65 at diagnosis. The majority of patients are over 70 years of age. The 5-year survival is estimated to be from 2% to 30%. The purpose of this comprehensive review of literature was to establish evidence-based guidelines for nurses and physicians caring for patients diagnosed with cholangiocarcinoma. The specific aims were to assist physicians and nurses in implementing evidence-based care through an understanding of cholangiocarcinoma patients undergoing, surgery, chemotherapy, radiation therapy, or a clinical trial, and to be able to manage symptoms of biliary obstruction, and toxicities from treatment.

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