Abstract

Background: Since the landmark randomized trial of thymectomy in myasthenia gravis (MGTX), total thymectomy is considered standard of care in conjunction with medical management for myasthenia gravis (MG). We aim to report the incidence of thymomatous MG in our population, tumor histopathological characteristics, and background thymus tissue histopathological characteristics in comparison to those without MG. We also compared MG remission rate for thymomatous versus non-thymomatous MG. We hypothesize that the background thymus tissue in thymomatous MG differs than non-thymomatous MG with respect to volume of germinal centers, and that histology of thymoma in those with MG differs from those without MG.

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