Abstract
This report presents the implementation of a web tool for the extension of exposure-and toxicokinetic-toxicodynamic analysis that has been developed under aspecific EFSA request to Open Analytics under the framework agreement (OC/EFSA/AMU/2015/02).An open source software has been developed in R as a WEB-based tool including different components for the modelling of toxicokinetic (TK) and toxicodynamic (TD) processeswithin a structuredworkflow. The workflow provides the steps to perform such TK-TD modelling for single chemicals in the human health, animal health and ecological risk assessment. The web-based tool results in the implementation of four modules: (1) Chemical specific modules, (2) Physiological and life cycle trait modules, (3) Toxicokinetic module, and (4) Toxicodynamic module.
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