Abstract
A month-of-birth (MOB) effect has been shown in multiple sclerosis (MS). Our chi(2) analyses looked at whether this MOB effect differed by MS phenotype ("bout onset," "primary progressive"). The MOB effect was derived from "bout onset" MS patients (May/November ratio = 1.43; chi(2) = 17.32, df = 1, p = 0.000032). An unspecified environmental effect in early development can influence both multiple sclerosis susceptibility and phenotype.
Published Version
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