Abstract

There is a shift in critical care to adopt volatile anaesthetics as sedatives for certain patients using mechanical ventilation. Accompanying this shift is a growing body of literature describing the advantages or disadvantages of using isoflurane or sevoflurane for long term sedation. This practise requires a cost effective, efficient and safe means to deliver these drugs that can simultaneously operate with modern critical care ventilators and ventilation protocols while protecting the care environment and care workers from excessive exposure to the drugs. The anaesthetic conserving device (“AnaConDa”, Sedana Medical) is one device that delivers a safe sedative dose of either isoflurane or sevoflurane to a patient using existing critical care ventilators, common syringe pumps and gas monitors. The device is essentially a small disposable anaesthetic vaporizer and HME filter combined into one airway component. Similar to an HME filter, the device reflects moisture back to the patient, but also reflects 90% of the anaesthetic by adsorbing and releasing the drug using a proprietary carbon filament reflecting medium. This reflection reduces the total amount of anaesthetic needed, reducing that which is exhausted or scavenged upon exhalation. It can be used for 24 h of sedation, and fits into current critical care ventilator circuits almost without modifications. This article will describe the physical characteristics of the device, how it works, its development history and the performance parameters under which it can be used.

Highlights

  • The anaesthetic conserving device, “AnaConDa” (Sedana Medical, Danderyd Sweden) is a simple, disposable, class IIa device that allows the inhaled anaesthetics isoflurane and sevoflurane to be safely and efficiently vaporized and delivered utilizing any non-rebreathing mechanical ventilator.Sedana Medical, The Village Center, Two Mile House, Naas, Co

  • An anaesthetic gas monitor, a ventilator and syringe pump can be used with this device to deliver isoflurane or sevoflurane at safe sedative doses to a patient in critical care

  • The evaporator is made of a porous polypropylene extruded rod. It is pressed into a mount securing it within the housing and connecting it to the polyethylene agent line that supplies it with liquid isoflurane or sevoflurane from the syringe

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Summary

Introduction

The anaesthetic conserving device, “AnaConDa” (Sedana Medical, Danderyd Sweden) is a simple, disposable, class IIa device that allows the inhaled anaesthetics isoflurane and sevoflurane to be safely and efficiently vaporized and delivered utilizing any non-rebreathing mechanical ventilator. An anaesthetic gas monitor, a ventilator and syringe pump can be used with this device to deliver isoflurane or sevoflurane at safe sedative doses to a patient in critical care. The AnaConDa differs from HME filters in having a second layer comprised of a 3–4 mm thick pad of activated carbon felt This proprietary carbon felt is capable of adsorbing and releasing isoflurane or sevoflurane vapor. The evaporator is made of a porous polypropylene extruded rod It is pressed into a mount securing it within the housing and connecting it to the polyethylene agent line that supplies it with liquid isoflurane or sevoflurane from the syringe. When the bottle is empty, the adaptor can be unscrewed and placed on the full bottle

Agent concentration
HME performance
Airway resistance
Titration
Contraindication
CO2 reflection
Environmental exposure
Findings
Conclusion
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