Abstract

BackgroundDepression is most common among the elderly and is associated with major impairment. With limited accessible treatments available, remotely provided interventions are needed. Internet-based interventions have been proven effective for a number of mental and somatic health problems. However, the elderly population has received relatively limited attention in previous studies. This study aims to address this gap by investigating the effectiveness of a tailored Internet-delivered modular intervention based on cognitive behavioral therapy (CBT).MethodsA minimum of 60 participants will be recruited and randomly assigned to groups in a two-armed parallel controlled trial with a waiting list. The intervention group will have access to an 8-week therapist-supported modular intervention. The waiting list group will be instructed to wait for 8 weeks and then granted access to the intervention for 8 weeks. Pre, post, and 3-, 12-, and 24-month follow-up assessments are planned for measuring changes in depression symptoms, anxiety symptoms, and psychological well-being using PHQ-9, GDS, GAD-7, and WHO-5. Primary outcomes of all the participants will be analyzed using the intention-to-treat principle, and within- and between-group effect sizes will be calculated.DiscussionInternet-based interventions could help address the existing treatment gap for depressed older adults. However, to date, the effectiveness of Internet-based CBT (ICBT) for depressed older adults has only been tested in a few studies. This trial will demonstrate if Internet-based CBT is effective for this population when compared to a waiting list control. Further analysis of secondary outcomes and participant behavior in the intervention will potentially reveal effectiveness moderating factors.Trial registrationClinicalTrials.gov NCT04728204. Registered on 15 January 2021. https://www.clinicaltrials.gov/ct2/show/NCT04728204?term=NCT04728204&draw=2&rank=1

Highlights

  • Depression is most common among the elderly and is associated with major impairment

  • There was already an urgent need for effective remotely delivered psychosocial interventions for the elderly but the global COVID-19 pandemic has brought this urgency to new heights [35]

  • Internet-based interventions could help reduce barriers associated with access to mental health care [23]

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Summary

Introduction

Depression is most common among the elderly and is associated with major impairment. Internet-based interventions have been proven effective for a number of mental and somatic health problems. This study aims to address this gap by investigating the effectiveness of a tailored Internet-delivered modular intervention based on cognitive behavioral therapy (CBT). Depression is one of the most prevalent mental health disorders among the elderly [1, 2] and has been reported as one of the three largest contributors to the global burden of disease [3]. Among individuals aged 65 to 100 years, 2.7% of men and 4.4% of women have major depression [5]. Late-life depression has been associated with cognitive dysfunction, disability, medical illnesses, and social isolation [7]. Untreated depression can have serious implications on the quality and quantity of life [8]

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