A study to evaluate comparative efficacy of two different venous occlusion duration on pretreatment with Inj. lignocaine to prevent propofol Inj. pain in patients undergoing surgery under general anaesthesia

Abstract

Aim: To study the efficacy of two different time duration of venous occlusion in preventing propofol injection pain. Materials and Methods: In this prospective, randomized controlled study patients of either gender, scheduled to undergo elective surgery under general anaesthesia were randomly assigned into 2 groups (Group L30 and Group L60) of 25 patients each. Group L30 and Group L60 received Injection (Inj) Lignocaine 40mg intravenously under venous occlusion for 30 seconds and 60 seconds respectively followed by Inj propofol for induction. propofol induced pain was assessed after administration of 25% of total calculated dose of propofol. Results: In our study, significantly more patients in Group L30 (72%) reported pain as compared to Group L60 (32%). (p < 0> Considering the severity of pain, in Group L30, out of 72% who had pain; 64% had mild pain and 8% had moderate pain. Whereas in Group L60, 32% had pain and all had mild pain only. Conclusion: The study found that pretreatment with Inj Lignocaine 40 mg under venous occlusion for 60 seconds followed by Inj propofol for induction significantly reduced the incidence and the severity of pain of propofol injection when compared with the group who received 40 mg of Inj. Lignocaine under venous occlusion for 30 seconds. Keywords: Propofol injection, Pain, Local anesthetic, Lignocaine, Venous occlusion.