Abstract
Background Radiotherapy of nasopharyngeal carcinoma (NPC) often delivers considerable radiation dose to the temporomandibular joint (TMJ). This may lead to radiation-induced trismus, which can have impact on the quality of life of post-radiotherapy (post-RT) patients. However, the exact cause of trismus and its relationship with dose has not been fully understood. This study aimed to evaluate the quantitative relationship between severity of post-RT trismus and TMJ doses and other patient characteristics. Through ultrasound examination, this study also aimed to identify factors affecting morphological changes of TMJ.
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