A Study of Quality of Life in Patients with Vitiligo in A Tertiary Care Centre in Marathwada Region

Abstract

Introduction: Vitiligo is an acquired idiopathic skin disorder characterized by loss of inherited complexion of skin and mucosa resulting in white patches. Although there is no physical impairment, vitiligo may significantly affect quality of life and psychological well-being. Unpredictable course of vitiligo and uncertainty of treatment make patients more vulnerable to hopelessness and depression. Aim: To assess the quality of life and level of depression in patients suffering from vitiligo and its relation to various demographic and clinical parameters. Material and methods: A cross-sectional observational study, consisting 92 patients diagnosed as vitiligo, was carried out in outpatient department of Dermatology in a tertiary care centre, Aurangabad, Marathwada region. After noting demographic and clinical parameters, patients were asked to fill Vitiligo Impact Scale (VIS) and interviewed with Hamilton Depression Rating Scale (HAM-D) questionnaires. Mean VIS and HAM-D scores were compared with various demographic and clinical variables. Statistical analysis was done using SPSS20. Results: Our study revealed that younger and middle age patients suffered from more depression and had higher impact on quality of life. Women in general had greater impact on quality of life and level of depression. Education plays an important role in alleviating anxiety associated with disease. Generalized and progressive vitiligo was more distressing for patients. Conclusion: Objective scoring systems such as VIS and HAM-D should be used routinely to measure impairment of quality of life and to assess level of depression. These findings should be incorporated into therapeutic decision-making.