Abstract
It is well known that histamine is the most important chemical mediator of nasal allergy, and histamine hypersensitivity of the nasal mucosa has been also recognized in the patients with nasal allergy. Therefore, the degradation or inactivation of histamine released from basophilic cells following reaginic antigen-antibody reaction is very important in the patients from a view point of the defence mechanism of the body. The purpose of this study is to investigate the levels of plasma histaminase of allergic patients both in pollen season and in season without pollen of Japanese cedar. The patients have developed clear symptoms due to allergen challenge during the pollen season. Higher plasma histaminase activity was revealed in pollen season than that out of season. Furthermore, close relations were recognized among the plasma histaminase activity and nasal symptoms, local findings, eosinophils in nasal secretion, and histamine sensitivity of nasal mucosa during the pollen season.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
