Abstract
Avian leukosis viruses of subgroups B, D, F, and one strain of reticuloendotheliosis virus (REV) are able to make plaques in several lines of chick embryo fibroblasts. Moreover, plaque formation with some strains of subgroup A is obtained only in chicken fibroblasts of C C phenotype. One exception is RAV-3 which produces plaque in line 6 ( C E ) only. Several important steps for the reproducibility of the assay are described. Of all the vital stains tested, only neutral red incorporated into the agar overlay is capable of inducing the formation of plaques. Several lysosome stabilizers and labilizers are examined and their role in the mechanism of plaque formation is discussed.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
