Abstract
Aim: In this prospective study we analysed the incidence of carcinoma in patients operated with preoperative diagnosis of benign thyroid conditions, and correlate it with risk factors for further management. Methods: A prospective analysis of 94 patients that presented to a tertiary care centre in south India and diagnosed to have benign thyroid disease that required surgical management from April 2016 to October 2017. The postoperative thyroid specimen was analysed and any evidence of malignancy was noted. These patients were further evaluated and need for further treatment was analysed based on risk factors like advanced age, male sex and size of the tumour according to AGES, AMES and MACIS scoring systems. Results: In our study, 11 out of 94 patients operated for benign thyroid disease were found to have malignancy. Thus, the incidence of occult carcinoma of thyroid was significantly higher than that of the previously published literature in India, 11.7% vs 2-7%. The most common preoperative diagnosis was that of multinodular goitre. Conclusion : The incidence of malignancy in benign thyroid specimens was high in our study, but there is a need for longer follow up, to study the biology and behavioural patterns of these probably low grade tumours.
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