A simplified technique using chymotrypsin lavage for the cytological diagnosis of gastric cancer.

Abstract

CancerVolume 8, Issue 6 p. 1137-1141 ArticleFree Access A simplified technique using chymotrypsin lavage for the cytological diagnosis of gastric cancer Cyrus E. Rubin M.D., Cyrus E. Rubin M.D. Departments of Medicine and Pathology, University of Chicago, Chicago, Illinois; and the Department of Medicine, University of Washington, Seattle, WashingtonSearch for more papers by this authorEarl P. Benditt M.D., Earl P. Benditt M.D. Departments of Medicine and Pathology, University of Chicago, Chicago, Illinois; and the Department of Medicine, University of Washington, Seattle, WashingtonSearch for more papers by this author Cyrus E. Rubin M.D., Cyrus E. Rubin M.D. Departments of Medicine and Pathology, University of Chicago, Chicago, Illinois; and the Department of Medicine, University of Washington, Seattle, WashingtonSearch for more papers by this authorEarl P. Benditt M.D., Earl P. Benditt M.D. Departments of Medicine and Pathology, University of Chicago, Chicago, Illinois; and the Department of Medicine, University of Washington, Seattle, WashingtonSearch for more papers by this author First published: 1955 https://doi.org/10.1002/1097-0142(1955)8:6<1137::AID-CNCR2820080608>3.0.CO;2-7Citations: 24AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL References 1 Benditt, E. P., and French, J. E.: Histochemistry of connective tissue: I. The use of enzymes as specific histochemical reagents. J. Histochem. & Cytochem. 1: 315– 320, 1953. 2 Benditt, E. P., and French, J. E.: Unpublished observations. 3 Hinkel, E. T., Jr.: The effect of chemical treatment of papaya latex on the initial activity and stability of papain. Ann. New York Acad. Sc. 54 (Art. 2): 255– 262, 1951. 4 Hinkel, E. T. Jr.: The effect of the temperature of drying papaya latex on the initial activity and stability of papain. Ann. New York Acad. Sc. 54 (Art. 2): 245– 254, 1951. 5 Hinkel, E. T., JR.: Further studies on the effect of drying conditions and of the chemical treatment of papaya latex on the stability of papain. Ann. New York Acad. Sc. 54 (Art. 2): 263– 272, 1951. 6 Hwang, K., and Ivy, A. C.: A review of the literature on the potential therapeutic significance of papain. Ann. New York Acad. Sc. 54 (Art. 2): 161– 207, 1951. 7 Klayman, M. E., and Massey, B. W.: Personal communication. 8 Morton, J. A., and Pickles, M. M.: Use of trypsin in the detection of incomplete anti-Rh antibodies. Nature 159: 779– 780, 1947. 9 Panico, F. G.; Papanicolaou, G. N., and Cooper, W. A.: Abrasive balloon for exfoliation of gastric cancer cells. J. A. M. A. 143: 1308– 1311, 1950. 10 Rosenthal, M.: Personal communication. 11 Rosenthal, M., and Traut, H. F.: The mucolytic action of papain for cell concentration in the diagnosis of gastric Cancer 4: 147– 149, 1951. 12 Rous, P., and Jones, F. S.: A method for obtaining suspensions of living cells from the fixed tissues, and for the plating out of individual cells. J. Exper. Med. 23: 549– 555, 1916. 13 Rubin, C. E.; Massey, B. W.; Kirsner, J. B.; Palmer, W. L., and Stonecypher, D. D.: The clinical value of gastrointestinal cytologic diagnosis. Gastroenterology 25: 119– 138, 1953. 14 Simms, H. S., and Stillman, N. P.: Substances affecting adult tissue in vitro. I. The stimulating action of trypsin on fresh adult tissue. J. Gen. Physiol. 20: 603– 619, Pl. 1, 1937. Citing Literature Volume8, Issue61955Pages 1137-1141 ReferencesRelatedInformation