Abstract
Guiera senegalesis (G. senegalensis) Family Combretaceae is shrubs or trees widely distributed in west and central Africa. In traditional medicine G. senegalensis used to treat malaria, dysentery and/or diarrhea, cough and/ cold, abdominal pains, leprosy, hypotension and hypertension, diabetes, snakebites eczema, impotence, epilepsy, breast cancer, depressant and jaundice. Phytochemical screening investigated by scientists showed the presence of alkaloids, flavonoids, tannin, saponin, terpinoids/sterols and cardionolics mainly in leaves and roots of the plant. The biological activities showed positive results as anti-tuberculosis, anti-diarrhoeal, anti-plasmodia, analgesic and devoid of anti-inflammatory, antifungal, antioxidant anti-lipid peroxidation activity, anti-malaria and with low toxicity, antifungal, anti-acetylcholinesterase, antilipid peroxidation in rat’s brain homogenate, erythrocytes hemolysis inhibitory activities and antitussive activities. The review revealed the importance of G. senegalensis as a natural therapy and recommend for further study and the work of the pharmaceutical formulation.
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