Abstract

Cancer mainly defined as a group of diseases lead to growth of abnormal cells anywhere in the body. Anything that potentially leads to the growth of abnormal cells in the body is called cancer. Cancer cells grow with potential to invade or spread in any parts of the body. Cancer can be caused by various agents and factors depending upon the type of cancer developed in the particular region. Chemical and toxic substance exposure, ionizing agents and genetic factors are majorly responsible for developing cancer cells in the body state or degree of disease is determined by medical uses such as biopsy which helps in diagnosis of cancer and determining its types and extent of cancer cells spread throughout the body. The molecular targets such as VEGF, oestrogen, protease activated receptor, BRAF has become major innovations towards drug discovery both naturally and chemically.Symptoms of cancer varies according to the types and extent of disease developed in body symptoms like fatigue, weight loss, change in bowel and bladder function, cough and skin tone are some of the early signs of developing cancerous cells in the body. In this study, we focussed the targets of leading cancers among male and female like breast cancer, lung cancer and colon cancer in drug discovery and development.

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