Abstract
Edible mushrooms have emerged as a compelling subject of study in the context of cancer therapy due to their potential anticancer properties. This review paper comprehensively examines the significance of edible mushrooms in cancer treatment, elucidates their mechanisms of action, presents findings from preclinical and clinical studies, discusses the safety and side effects of mushroom consumption, and explores dietary recommendations and integrative approaches. Key bioactive compounds within mushrooms, such as beta-glucans, polysaccharides, and lectins, are scrutinized for their roles in modulating immune responses, apoptosis induction, and antioxidant effects. Clinical trials involving mushroom interventions are summarized, offering insights into their effectiveness and safety. Safety considerations are addressed, with a focus on potential side effects, contraindications, and comparative safety with conventional cancer treatments. The paper also highlights the importance of integrating edible mushrooms into cancer care strategies, both as dietary components and complementary therapies. Potential synergies between mushrooms and other natural remedies, such as probiotics, are explored. This review concludes by emphasizing the promising prospects of edible mushrooms in cancer treatment, calling for further research, and advocating for their informed inclusion in holistic cancer care.
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