Abstract
Globally, more than 10 million people are affected every year by acute kidney injury (AKI) and approximately 6% of hospital patients sustain some degree of kidney injury during their hospital event. Reducing perioperative kidney injury may significantly improve patient outcomes. As perioperative physicians, we are in a position to have some influence on renal outcomes.This article is a review of the current literature on the relevance of renal protection, definitions, mechanisms and new biomarkers of AKI, as well as improved renal perfusion strategies. It specifically considers the renal effects of general and regional anaesthesia, intra-abdominal pressure and abdominal compartment syndrome. The usefulness of certain drugs is investigated. Mechanisms of injury by nephrotoxins, as well as strategies to minimise these injuries, are discussed. Intravenous fluids are briefly mentioned as they relate to renal function.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Southern African Journal of Anaesthesia and Analgesia
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
