A retrospective study of 100 cases of focal vitiligo treated by autologous, noncultured melanocyte-keratinocyte cell transplantation

Abstract

<p class="abstract"><strong>Background:</strong> <span>Vitiligo is a common skin disease affecting 1%-2% of general population. Even though different modalities of treatment available, it remains as a difficult disease to treat. Many cases remain stable after a period of medical therapy without any further response. Surgical techniques are the only hope in such patients.<span class="apple-converted-space"> The </span>aim of this study was to evaluate the response of<span class="apple-converted-space"><strong> </strong></span>autologous, noncultured melanocyte keratinocyte cell transplantation in patients with stable focal vitiligo</span><span lang="EN-IN">.</span></p><p class="abstract"><strong>Methods:</strong> <span>A retrospective study of 100 cases focal vitiligo treated by autologous, noncultured melanocyte-keratinocyte cell transplantation. Serial of photographs were taken on each visit. The patents were followed for a period of 5 years. The results were analyzed on a visual analogue scale</span>.<strong></strong></p><p class="abstract"><strong>Results:</strong> <span>Out of total 100 patients, 44 had excellent (90 to 100%) response, 18 had good (60 to 89%) response, 12 had fair (25 to 59%) response and 26 had poor response (0 to 24%). Age and sex of the patients and size and duration of lesions, did not show significant influence on results of transplantation</span><span lang="EN-IN">. </span></p><p class="abstract"><strong>Conclusions:</strong> <span>This is a simple, safe, and effective surgical therapy for replenishing the missing melanocytes in resistant cases of vitiligo. Repigmentation lasts long with very good cosmetic acceptability</span><span lang="EN-IN">.</span></p>