Abstract
Introduction: Inflammatory myofibroblastic tumors (IMTs) arising in the mediastinum is rare. Their etiology remains unknown and their diagnosis is often overlooked before the use of surgery which allows the proper diagnosis and adequate treatment.Case report: We report a case of the 56-year-old woman that had a mediastinal mass discovered after a long complaint of chest discomfort. Chest contrast-enhanced computed tomography (CT) showed a heterogeneously enhanced mass in the middle mediastinum The diagnosis was confirmed by histopathology and immunohistochemical study after surgical resection through a thoracotomy The patient was well and had no recurrence 6 months after surgery.Conclusion: The diagnosis of IMT should be kept in mind and included in the differential diagnosis of mediastinal masses.
Highlights
Inflammatory myofibroblastic tumors (IMTs) arising in the mediastinum is rare
Chest contrast-enhanced computed tomography (CT) showed a heterogeneously enhanced mass in the middle mediastinum The diagnosis was confirmed by histopathology and immunohistochemical study after surgical resection through a thoracotomy The patient was well and had no recurrence 6 months after surgery
Inflammatory myofibroblastic tumor (IMT) is a rare benign tumor that most commonly occurs in the lung and orbit [1]
Summary
Inflammatory myofibroblastic tumor (IMT) is a rare benign tumor that most commonly occurs in the lung and orbit [1]. CASE REPORT A 56 year old women with a history of right thoracic discomfort for 3 months, was reffered to our department for further evaluation and eventual surgical treatment. Chest contrast-enhanced computed tomography (CT) (figure 2) showed a heterogeneously enhanced irregular mass in the middle mediastinum ; The tumor had no calcification. The tumour was composed of admixture of prominent chronic inflammatory cells including lymphocytes, plasma cells and histiocytes, and spindle-shaped cells with pale eosinophilic cytoplasm, oval nuclei, fine chromatine and inconspicuous nucleoli It was positive for vimentine (figure 6A), ALK-1 (figure 6B) and negative for CD34. During the operation it was found that the tumor located in the Barety lodge, encapsuled and firmly adherent to surounding tissues (figure 3)
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