Abstract
A primary pleural based marginal zone low grade NHL is very rare. Primary pleural Lymphomas account for less than 0.5% off all Non-Hodgkin Lymphomas and DLBCL is the most common subtype of primary pleural lymphomas. Here, we report a rare case of marginal zone lymphoma of low grade with Mib index of 15-20% presenting as a pleural based mass in a middle age individual. A 52 years old male presented with right sided pleural effusion with pleural thickening of soft tissue density. Thoracoscopy showed pleural based mass lesion and pleural biopsy revealed low grade marginal zone NHL which is very rare with very few cases documented till date. Diagnosis was based on Bcl-2 and CD20 marker positivity on IHC. Treatment of such Low-grade Marginal zone lymphoma is with Bendamustine and Rituximab.
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