Abstract

Mesalazine is a commonly used first-line therapy to treat acute mild to moderate ulcerative colitis (UC). Myocarditis is a rare complication of inflammatory bowel disease. This is a case report of a 19-year-old female with myocarditis induced after commencing mesalazine for UC. She was admitted with pleuritic-type chest pain associated with severe dyspnoea and was hemodynamically unstable during admission. She had elevated troponin and N-terminal pro-B-type natriuretic peptide. Transthoracic echocardiogram (TTE) results suggested there was evidence of myocarditis with reduced ejection fraction, which was later confirmed by cardiac magnetic resonance imaging. There was a rapid improvement of cardiac status after stopping mesalazine within two weeks.

Highlights

  • Inflammatory bowel disease (IBD) is a disorder causing chronic inflammation of the gastrointestinal tract

  • Myocarditis is a rare complication of inflammatory bowel disease

  • This is a case report of a 19-year-old female with myocarditis induced after commencing mesalazine for ulcerative colitis (UC)

Read more

Summary

Introduction

Inflammatory bowel disease (IBD) is a disorder causing chronic inflammation of the gastrointestinal tract. Based on the results of flexible sigmoidoscopy and biopsy, the diagnosis of moderate UC was established and a maximum dose of oral mesalazine 2.4 grams a day and a tapering dose of oral prednisolone (starting at 30 mg OD) were prescribed She responded well to treatment, reporting improved abdominal symptoms. There was an elevated cardiac troponin-T enzyme of 64 ng/ml (laboratory normal of

Discussion
Conclusions
Findings
Disclosures
Brown G

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.