Abstract
AbstractA multicenter, phase 4, randomized, comparative‐efficacy study in subjects with lower extremity wounds was carried out to compare wound closure rates, for a single‐use negative pressure wound therapy (s‐NPWT) versus traditional NPWT (t‐NPWT) systems over a 12‐week treatment period. From the initial population of patients with diabetic foot ulcers (DFU) and venous leg ulcers (VLU), we analyzed a subgroup of patients with diabetes mellitus and leg and foot ulcers (either DFUs or VLUs in diabetics), termed, the diabetic lower extremity ulcers (DLEU). In the DLEU group, there were 95 patients in intention‐to‐treat (ITT) and 61 patients in per protocol (PP) populations, respectively. We found a significant difference in favor of s‐NPWT over t‐NPWT in the confirmed wound closures at 12 weeks both in ITT (p < 0.001) and PP populations (p = 0.017). Significantly higher wound closure rates in s‐NPWT group suggest that s‐NPWT should be preferred NPWT option for DLEU.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.