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Abstract
The purpose of this study was to analyze the advantages of TCR gene and its relationship with tumor infiltrating lymphocytes (til) and circulating tumor cells (CTCs). The properties of EpCAM and EGFR lipid magnetic microspheres were analyzed. The levels of Programmed cell death 1 ligand 1, B7-H3 and B7-H4 in peripheral blood were measured by quantitative immunofluorescence (QIF). T cell receptor expression profile and clone proliferation were detected. The prepared EpCAM and EGFR lipid magnetic microspheres showed good stability and specificity. The therapeutic method proposed in this study is expected to be applied.
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