Abstract
The feasibility of direct infusion analysis in a Fourier-transform ion cyclotron resonance mass spectrometer (FT-ICR MS) for fast differentiation and authentication of traditional Chinese herbal medicines (TCHMs) was evaluated for the first time. The widely used Gardenia jasminoides Ellis and the clinical preparations Kudiezi injection were selected as model samples and analyzed by this method. With minimal or no sample pretreatment, 30 and 29 peaks which were corresponding to 43 and 40 chemical constituent respectively were rapidly detected and tentatively identified according to the accurate mass information and MS/MS data within only few minutes, including iridoids, phenolic acids, glucosides, flavonoids, nucleosides and sesquiterpene lactones. Our results demonstrated that direct infusion analysis in FT-ICR MS could provide a rapid, solvent saving and environmental friendly method for the differentiation and authentication of TCHMs, and it may be applicable to other plants.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
