Abstract
The meiotic spindle plays important roles in the oocyte during chromosome alignment and segregation at meiosis. It is well known that a higher rate of chromosomal abnormality occurs in human oocytes compared with other animal oocytes. However, the cause of the high incidence of chromosomal abnormality in human oocytes is not clearly understood. In this study, using time-lapse observations, we studied differences of chromosomal movement during first and second meiosis in human and mouse oocytes.
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