Abstract
A simple and sensitive electrochemical sensor for detection of dopamine has been developed based on ionic liquid functionalized graphene oxide supported gold nanoparticles (GO-IL-AuNPs) coated onto a glassy carbon electrode.
Highlights
Dopamine (DA) is a catecholamine neurotransmitter secreted by the brain that plays a critical role in maintaining the functional activities of many organs, such as the heart, brain and kidney.[1,2,3] Dopamine can directly affect human emotions, learning and memory ability
The gold nanoparticles were stored in a refrigerator at 4 C. 10 mL of gold nanoparticles was added into 20 mL of Graphene oxide (GO)-Ionic liquids (IL) hybrid solution, and ultrasonic treatment for 30 min produced the GOIL-AuNPs composite
The results indicate that GO has been combined with the ionic liquid
Summary
Dopamine (DA) is a catecholamine neurotransmitter secreted by the brain that plays a critical role in maintaining the functional activities of many organs, such as the heart, brain and kidney.[1,2,3] Dopamine can directly affect human emotions, learning and memory ability. GO-based materials gra ed onto noble metal nanoparticles have attracted considerable interest owing to their exible structure, excellent catalytic capabilities and excellent electron transport properties.[25] Recently, gold nanoparticles have been considered as an attractive candidate because of their huge speci c surface area, excellent biocompatibility, good chemical stability and outstanding conductivity and catalytic properties. Combining the advantageous features of gold nanoparticles and ionic liquid functionalized graphene oxide, the nanocomposites could incur synergy on electrochemical properties and improve the sensitivity of the nanomaterials. With a huge speci c surface area and a large quantity of oxygen groups, GO shows good adsorption of dopamine These oxidized areas on the GO plane break the long-range conjugated network and p-electron cloud, leading to a degradation of carrier mobility and conductivity. The results indicated that the proposed sensor could achieve simple and efficient detection of dopamine
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