A Novel Approach for the Measurement of pH of Body Fluids at Various Temperatures Using Compensation Technique

Abstract

AbstractThe pH is the negative base 10 logarithm of the hydrogen ion concentration. The hydrogen ion (H+) activity is measured and an electrical potential is produced by the pH electrode. The pH electrode is based on the principle of voltage that is developed as two liquids having different pH at either sides of a thin glass membrane is contacted. The most chemical and biological reactions are governed by the hydrogen ion activity. The pH of the body fluids in human plays an important role. Either increase or decrease in its value leads to many diseases such as respiratory alkalosis, brain injury, lung cancer, and kidney stone. The practically used electrodes will not be ideal and has true output that deviates from zero mV. The variation is called the electrode offset error. Also, the pH of any solution will rely upon temperature. Therefore, a pH electrode and temperature compensator have been designed. The electrode output varies linearly to the changes in pH of the solution. pH-based applications require temperature compensation to provide accurate pH values.KeywordspHTemperatureBody fluidsCompensation technique