Abstract
In this study, a new real-time measurement technique for the characterization of the water leaching behavior of space holding particles from titanium scaffold preform for bone tissue engineering was developed. This technique yielded accurate and reproducible data. Fitting the data acquired into the existing solvent debinding models led to plots that could be used to elucidate the mechanisms operating during the space holder removal process through water leaching, i.e., (i) rapid dissolution, (ii) dissolution and diffusion and (iii) saturation.
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