Abstract
Origin of Life What were the chemical reaction networks that enabled the emergence of life on Earth? Many previous studies have investigated the likely chemistry of these networks; for example, postulating an earlier RNA world that paved the way to today's living systems. In a Perspective, Cronin and Walker argue that elucidating the network properties, rather than the detailed chemistry, is key to understanding how life began. Further insight may come from characterizing the emergence of life as a phase transition and asking fundamental questions about what it means for a physical system to be alive. By challenging current models, scientists may not only understand how life as we know it originated but may also be able to detect or create different forms of life. Science , this issue p. [1174][1] [1]: /lookup/doi/10.1126/science.aaf6310
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