Abstract
This study was aimed to investigate the early clinical outcomes of small-incision lenticule extraction (SMILE) to correct both myopia and myopic astigmatism at major clinical centers in Japan. This case series consisted of two hundred fifty-two eyes of 130 consecutive patients who underwent SMILE surgery (29.5 ± 6.3 years, mean age ± standard deviation), with spherical equivalents of −4.33 ± 1.61 D. We determined the safety, efficacy, predictability, stability, and adverse events of this procedure. Corrected distance visual acuity significantly improved, from −0.18 ± 0.04 preoperatively to −0.19 ± 0.07 logMAR postoperatively (paired t-test, p < 0.001). Uncorrected distance visual acuity also significantly improved, from 1.05 ± 0.26 preoperatively to −0.15 ± 0.11 logMAR postoperatively (p < 0.001). 88% and 98% of eyes were within ± 0.5 and 1.0 D of the targeted correction, respectively. Changes in manifest spherical equivalent from 1 week postoperatively were 0.02 ± 0.35 D (p = 0.127). No vision-threatening complications were observed in any of the cases. SMILE performed well in the correction of myopic refractive errors, and we experienced no severe complications in this series, indicating its feasibility as a surgical option for the treatment of these eyes.
Highlights
This study shows that small-incision lenticule extraction (SMILE) performed well in all measures of safety, efficacy, and predictability for the correction of myopia and myopic astigmatism, and that no severe complications occurred in any of the cases
To the best of our knowledge, this is the first multicenter study to investigate the visual and refractive outcomes and the adverse events of SMILE in a large number of patients presenting at major clinical centers in Japan
Our outcomes were assumed to be less dependent on the individual surgical skills and experiences of refractive surgeons, and were clinically helpful for understanding the whole image of SMILE in Japan
Summary
This study was aimed to investigate the early clinical outcomes of small-incision lenticule extraction (SMILE) to correct both myopia and myopic astigmatism at major clinical centers in Japan. The objective of this study is to retrospectively assess the early outcomes of SMILE for myopic refractive errors, in a cohort of patients presenting at major institutions in Japan
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