Abstract
But de la presentation Substantial molecular evidence suggests a role for human papillomavirus (HPV) in the pathogenesis of laryngeal squamous cell carcinoma (LSCC), but epidemiologic and prognosis data have been inconsistent in a Chinese population. Materiel et methodes This multicenter and case control study included 674 LSCC patients and 674 control patients treated in three centers in Shanghai from 2006 till 2013. We used immunohistochemistry (IHC) and GenoArray genotyping assay to evaluate the HPV infection status and determined its prevalence and influence on disease prognosis. Resultats The total prevalence of HPV DNA was 4,9 % (33/674) in LSCC patients and 0 % (0/674) in control cases in our series (P Conclusion A very low prevalence of HPV was among LSCC patients in a Chinese population. HPV was more common in nonsmokers, non-drinkers and supraglottic LSCC patients. The presence of HPV DNA was not associated with patients’ overall survival and disease progression-free rate in our series.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
