Abstract

SummaryThe distribution of lysosomal enzymes in conceptuses during resorption induced by ovariectomy was studied by histo-chemical methods. The histologic changes associated with ovariectomy-induced resorption were, in sequence, disruption of the maternal-fetal blood barrier (with mixing of fetal and maternal blood), simultaneous degeneration of the cells of the fetus, yolk sac, and placental labyrinth, and invasion of the fetal area with maternal blood. Histochemical study of acid phosphatase in the resorbing tissues showed a persistence of the lysosomes in the fetus, yolk sac, and placental labyrinth during tissue degeneration. There was a change in the distribution of the lysosomes in the fetal neural tube during the process of resorption.

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